子宮內膜癌150例臨床病例分析

子宮內膜癌150例臨床病例分析【摘要】目的：探討與子宮內膜癌術后生存率相關的因素。方法： 選擇2004年2月-2011年12月北京朝陽醫院經手術治療術后病理確診為 子宮內膜癌的患者150例，分析與子宮內膜癌術后生存率相關因素。結果: 年齡大于等于56歲的患者3年、5年生存率低于年齡小于56歲的患者（P<0. 05）；早期（I期、II期）患者的3年、5年生存率明顯高于晚期（III 期、IV期）患者（P<0.05）；組織分化較好的（Gl、G2）患者的3年、5年 生存率高于組織分化差的（G3）患者（"0.05）；肌層浸潤深度小于1/2 的患者的3年、5年生存率高于肌層浸潤深度大于等于1/2的患者（P<0. 05）o結論：子宮內膜癌術后患者的生存率與年齡、手術-病理分期、 組織分化、腫瘤肌層浸潤深度密切相關。故早期發現并診治子宮內膜癌能 明顯提高患者術后牛存率。【關鍵詞】子宮內膜癌；術后生存率中圖分類號R737. 33文獻標識碼B文章編號1674-6805 （2014）3-0152-03Clinical Analysis of 150 Cases with Endometrial Carcinoma/BU Shu-na. //Chinese and Foreign Medical Research, 2014, 12 （3）： 152-154 [Abstract ] Objective: To explore the factors related to postoperative survival rate of endometrial carcinoma. Method: Atotal of 150 patients with endometrial carcinoma underwent primary surgical treatment and con firmed by pathology from Feb 2004 to Dec 2011 in Beijing Chaoyang Hospital were selected, and the factors related to postoperative survival rate of endometrial carcinoma were analyzed. Result： The postoperative survival rates in 3 and 5 years of patients whose ages were greater than or equal to 56 years-old were lower than that of patients whose ages were less than 56 years-old (P<0. 05) . The postoperative survival rates in 3 and 5 years of pationts in the early stage (phase I and phase II ) were higher than that of patients in the latter period (P<0. 05) .The postoperative survival rates in 3 and 5 years of patients whose degrees of tissues differentiation (G1 and G2) were better were higher than that of patients whose degrees of tissues differentiation (G3) were bad (P<0. 05)? The postoperative survival rates in 3 and 5 years of patie nts whose muscular infilt ration dep th were less than 1/2 were higher than that of patients whose muscular infiltration depth were greater than or equal to 1/2(P<0.05)?Conelusion： Age, surgical-pathologic stage, tissue differentiation and the depth of tumor invasion are closely related to the postoperative survival rate of patients with endometrial carcinoma? So early discovery, early diagnosis and early treatment of patients with endometrial carcinoma can raise the postoperative survival rate.[Key words] Endometrial carcinoma； Postoperative survivalrateFirst-author" s address： The Maternal and Child Health Care Hospital of Bei jing Shunyi Districts , Beijing 101300, China子宮內膜癌(endometrial carcinoma)是原發于子宮內膜的上皮性 惡性腫瘤，為女性生殖器官常見的惡性腫瘤，在經濟發達國家其發病率居 婦科惡性腫瘤首位。在我國，近年來發病率亦明顯上升。子宮內膜癌的發 牛可自生殖年齡到絕經后，高峰發病年齡為50?69歲。與其他婦科惡性 腫瘤相比，大多數子宮內膜癌的病程發展相對緩慢，臨床癥狀出現早，容 易早期發現，多數患者在確診時病灶尚局限在子宮內，因而治療效果較好, 預后較佳［1］。本文通過對150例筆者所在醫院子宮內膜癌患者的臨床資 料進行分析，進一步了解與患者術后生存率相關的因素，爭取進一步提高 患者術后生存率，現報告如下。 1資料與方法1. 1 一般資料選擇2004年2月-2011年12月筆者所在醫院經手術治療術后病理確 診為子宮內膜癌的患者150例。年齡35?81歲,平均(55?88±9.95)歲, 年齡中位數為56歲。其中小于56歲患者75例，大于等于56歲患者75 例。1.2手術-病理分期與組織分級標準子宮內膜癌手術病理分期以FIG02009年分期法為標準，具體如下：I期癌局限于子宮體，I A期無或〈1/2肌層浸潤，IB期±1/2肌層浸潤;II期腫瘤累及宮頸間質，未超出子宮；III期腫瘤局部播散，IIIA期腫瘤累 及子宮漿膜和/或附件，IIIB期陰道和/或宮旁受累，IIIC期盆腔和/或腹主 動脈旁淋巴結轉移，nmici盆腔淋巴結轉移，iiic2腹主動脈旁淋巴結轉 移；IV期膀胱和/或直腸轉移，和/或遠